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doi: 10.3389/fphar.2021.659584 143 WuM.YangY.WangM.ZengF.LiQ.LiuW.et al

This issue needs to be addressed more thoroughly to establish whether clinical outcomes of analgesic tolerance, as well as side effects such as respiratory depression and constipation, could be altered by directly manipulating bias toward or against agonists with different internalization capacities

10.1038/s41419-019-1678-y 139 UrsiniF.MaiorinoM.GregolinC

How Amino Acids Support Healthy Thyroid Hormone Levels Research has found that an insufficient intake of dietary essential amino acids for long periods of time alters thyroid axis activity